Scientist Aranya (Jackie Coogan) (and as this is a movie he is of course a mad scientist) is conducting twisted human experiments using spider venom to create a race of indestructible and obedient women. Another scientist called Dr Masterson (Harmon Stevens) discovers the vile experiments and is driven insane. He escapes the asylum and forces a group of people including Richard Travis and Paula Hill back to Aranya's bizarre desert lair...
This isn't a very good film. It's very slow moving and dull though does have some enjoyable science weirdness and 1950s style sleazy exotica.
The main problem with this film though is the soundtrack, a short piece of music which is on continuous repeat throughout the movie and will make you irritable and on edge after five minutes.