Steve (John Agar) and Dan (Robert Fuller) head out into the desert to investigate some mysterious radiation readings. They encounter a cave that shouldn't be there then encounter a bizarre floating brain. Steve returns to his fiancé Sally (Joyce Meadows) but he has changed, for a start he is horny! He also has some maniacal plans to conquer the world. Steve indeed has been possessed by a giant alien brain and has the power to detonate atomic explosions with his mind.
Steve forces the world's powers to bow to him, he plans to use Earth to conquer his own home planet. Meanwhile, an agent from his planet contacts Sally and her father John (Thomas Browne Henry), he tells them Steve has been taken over by a criminal but there is a way to save him...
This isn't a bad film at all, though very low budget. The special effects are few and far between though are pretty effective, the brain itself looks like an overgrown bee. An interesting and fun story.