A theft takes place at a US government facility, unfortunately the theft is of some biological agents which have been developed at the facility, one of which (the Satan bug) could potentially wipe out all life in Earth! Former agent Lee Barrett (George Maharis) is bought in to lead the desperate effort to locate who is behind the theft and the weapons. Lee thinks the ringleader is still at the facility and is vindicated when Dr Hoffman (Richard Basehart) is followed and leads him to the weapons.
However, Hoffman is always one step ahead and a desperate race against time ensues across California, Lee assisted by Ann (Anne Francis), and Hoffman seems to have aides and henchmen all over the place...
A highly entertaining film with the tension continually ratcheted up and various swerves and surprises to keep the action fresh. The good cast do very well too. Well worth a watch.