Scientist (mad of course) Dr Brewster (Lugosi) has gone into hiding. The reason is because he conducted experiments on himself and is now stuck as a half-man half-ape!
Brewster tries to get his colleague Dr Randall (Henry Hall) to get him recently harvested human spinal fluid to try and cure him, Randall refuses as it would mean he has to kill. Instead, Brewster and his pet ape (Emil Van Horn) go and seeks victims for himself...
A creepy film, Lugosi plays a good role as the man driven to kill through sheer desperation. The make-up is also very well done. This isn't the best Lugosi film though by a long way but is a fun watch.